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Metabolites also interface with the immune system and modulate the production of cytokines that regulate inflammatory responses, and thereby influence systemic inflammation, which has been implicated in NDDs and several other conditions ( The endocrine pathway involves interactions between metabolites and their receptors, which can induce the secretion of hormones from enteroendocrine L cells and lead to indirect signaling to the brain through systemic circulation or vagal pathways

Second, and perhaps more useful as drug evaluation tools, are ERPs

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Dosing, titration, and storage details refer to approved branded products and their labeling

This helps the patient function better at work